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KMID : 1038220220490020141
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Archives of Plastic Surgery
2022 Volume.49 No. 2 p.141 ~ p.149
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Comprehensive Evaluation of the Current Knowledge on Breast Implant Associated-Anaplastic Large Cell Lymphoma
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Yoo Hyo-Kyung
Park Ji-Ung
Chang Hak
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Abstract
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Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a recently spotlighted T-cell origin non-Hodgkin’s lymphoma with an increasing incidence of over 800 cases and 33 deaths reported worldwide. Development of BIA-ALCL is likely a complex process involving many factors, such as the textured implant surface, bacterial biofilm growth, immune response, and patient genetics. As the incidence of BIA-ALCL is expected to increase, it is important for all surgeons and physicians to be aware of this disease entity and acquire thorough knowledge of current evidence-based guidelines and recommendations. Early detection, accurate diagnosis, and appropriate treatment are the foundations of current care.
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KEYWORD
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BIA-ALCL, breast implants, biofilm, immunity, genetics
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